ANT431 sodium
CAS No. ——
ANT431 sodium ( ANT 431;ANT-431 )
产品货号. M17103 CAS No. ——
ANT431 sodium is a novel, highly water-soluble metallo-β-lactamase (MBL) inhibitor with IC50 of 290 nM and 195 nM for NDM-1 and VIM-2.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称ANT431 sodium
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述ANT431 sodium is a novel, highly water-soluble metallo-β-lactamase (MBL) inhibitor with IC50 of 290 nM and 195 nM for NDM-1 and VIM-2.
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产品描述ANT431 sodium is a novel, highly water-soluble metallo-β-lactamase (MBL) inhibitor with IC50 of 290 nM and 195 nM for NDM-1 and VIM-2, shows a comparatively weak inhibitor of VIM-1 and IMP-1 (Ki of 14.6 and 4.15 uM, respectively); potentiate the activity of meropenem (MEM) against a broad range of MBL-producing carbapenem-resistant Enterobacteriaceae (CRE), restore its efficacy against an Escherichia coli NDM-1 strain in a murine thigh infection model.
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同义词ANT 431;ANT-431
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通路GPCR/G Protein
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靶点Antibacterial
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受体Antibacterial
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量308.28
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分子式C9H7N3NaO4S2
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称5-(pyridine-3-sulfonamido)thiazole-4-carboxylic acid, sodium salt
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Everett M, et al. Antimicrob Agents Chemother. 2018 Mar 12. pii: AAC.00074-18.
产品手册
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